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 Abstract Blotter for sale Designer drugs or new psychedelic substances (NPS) are a heterogeneous cluster of gear obtained through the modification of chemical structure of some natural product or drugs. NPS illicitly commercialized in blotter papers mimicking the foremost common variety of psychodelic drug consumption, with an excellent variability of colors and symbols, have for the most part magnified worldwide, as well as in Brazil, changing into a vital rising public health issue. During this study, we’ve got evaluated the presence and profile of NPS in blotters confiscated within the State of Santa Catarina, Brazil, over the amount of 2011 to 2017. The authority’s criminal forensics employees have performed gas chromatography-mass prism spectroscope (GC-MS) analyses so as to see the chemical composition of the blotters. Throughout the evaluated period, there was a substantial increase within the seizing of blotters events, from eighty seven in 2011, to 301 in 2016 and reaching 27